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Urothelial dysplasia and carcinoma in situ of the bladder

Hofstädter, Ferdinand ; Delgado, R. ; Jakse, G. ; Judmaier, W.


Urothelial cells were pepsin-extracted from paraffin-embedded specimens taken from human nontumorous bladder mucosa, dysplasia, and carcinoma in situ. After Feulgen staining for DNA, nuclei were measured with an integrating microdensitometer. The measurements show that normal urothelium consists mostly of diploid nuclei. Dysplasia means that there is a predominance of tetraploid DNA values, ...


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