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Postoperative adaptation of the small intestine after total colectomy and J-pouch-anal anastomosis

Lerch, M. M. ; Braun, J. ; Harder, M. ; Hofstädter, Ferdinand ; Schumpelick, V. ; Matern, S.


Twelve patients who underwent total colectomy and J-pouch-anal anastomosis were followed up to 3 years after surgery to evaluate the functional and morphologic changes of the small-bowel reservoir. Intestinal absorption was impaired for lactose in 18 percent, for D-xylose in 27 percent, and for 75SeHCAT in 83 percent. Morphologic changes in ileal-pouch specimens consisted of a marked flattening ...


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