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Cloning and characterization of a fourth human somatostatin receptor

Rohrer, L. ; Raulf, F. ; Bruns, C. ; Buettner, R. ; Hofstaedter, Ferdinand ; Schüle, R.


We have isolated a gene coding for a fourth human somatostatin (somatotropin release-inhibiting factor) receptor. This additional somatostatin receptor (hSSTR4) is specifically expressed in human fetal and adult brain and lung tissue. The deduced amino acid sequence of the receptor displays both sequence and structural homology to three cloned somatostatin receptors as well as to other members of ...


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