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Cloning and characterization of a second AP-2 transcription factor: AP-2 beta

Moser, M. ; Imhof, A. ; Pscherer, A. ; Bauer, R. ; Amselgruber, W. ; Sinowatz, F. ; Hofstädter, Ferdinand ; Schüle, R. ; Buettner, R.



Abstract

AP-2 has been characterized previously as a unique 52 x 10(3) M(r) transcription activator encoded by a single gene that is expressed in a restricted pattern during embryonic morphogenesis of the peripheral nervous system, face, skin and nephric tissues. Here we report the isolation of genomic and cDNA clones encoding for a second AP-2 related transcription factor, designated AP-2 beta. AP-2 beta ...

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