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The combined effects of high-energy shock waves and ionising radiation on a human bladder cancer cell line

Fickweiler, S. ; Steinbach, P. ; Wörle, K. ; Hofstädter, Ferdinand



Abstract

The effects of high-energy shock waves (HESW) generated by an experimental Siemens lithotripter in combination with 137Cs gamma-rays were examined in vitro. Proliferation after treatment of immobilised pellets of either single cells or multicellular spheroids of the bladder cancer cell line RT4 was determined using colony-forming assays and cell cycle analysis. Surviving and cell cycle fractions ...

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