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Upper tract urothelial carcinoma: a clinicopathologic study including microsatellite instability analysis

Blaszyk, Hagen ; Wang, Linan ; Dietmaier, Wolfgang ; Hofstädter, Ferdinand ; Burgart, Lawrence J. ; Cheville, John C. ; Hartmann, Arndt



Abstract

Urothelial carcinoma of the renal pelvis and ureter may develop as a manifestation of the hereditary nonpolyposis colorectal cancer syndrome that is characterized by mutations in a number of DNA mismatch repair genes and detectable as microsatellite instability. In this study, we examined microsatellite instability and the clinicopathologic features of urothelial carcinoma of the renal pelvis (n ...

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