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Microsatellite instability predicts poor short-term survival in patients with advanced breast cancer after high-dose chemotherapy and autologous stem-cell transplantation

Wild, Peter J. ; Reichle, Albrecht ; Andreesen, Reinhard ; Röckelein, Georg ; Dietmaier, Wolfgang ; Rüschoff, Josef ; Blaszyk, Hagen ; Hofstädter, Ferdinand ; Hartmann, Arndt


PURPOSE: The purpose is to define molecular prognostic factors in patients with advanced breast cancer treated with high-dose chemotherapy (HDCT) and autologous stem cell transplantation (ASCT). EXPERIMENTAL DESIGN: Thirty-nine patients with breast cancer and extensive lymph node (level III) and/or systemic metastases from a prospective single-center study of sequential HDCT/ASCT were studied. ...


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