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In situ expression patterns of melanoma inhibitory activity 2 in healthy and diseased livers

Hellerbrand, Claus ; Bataille, Frauke ; Schlegel, Jacqueline ; Hartmann, Arndt ; Mühlbauer, Marcus ; Schölmerich, Jürgen ; Büttner, Reinhard ; Hofstädter, Ferdinand ; Bosserhoff, Anja-Katrin



Abstract

Recently we identified a novel gene of the MIA gene family, melanoma inhibitory activity 2 (MIA2) and found that MIA2 mRNA is selectively expressed in hepatocytes. Here, we analyzed the in situ expression of MIA2 protein and mRNA in healthy and diseased livers to get first insights into the function of MIA2. METHODS: We analyzed liver tissue of patients with chronic hepatitis C (HepC) infection ...

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