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Molecular evidence for progression of nephrogenic metaplasia of the urinary bladder to clear cell adenocarcinoma

Hartmann, Arndt ; Junker, Kerstin ; Dietmaier, Wolfgang ; Schröder, Sören ; Lopez, Diego ; Hofstädter, Ferdinand ; Blaszyk, Hagen



Abstract

Nephrogenic metaplasia or nephrogenic adenoma of the urinary tract may present a diagnostic challenge in surgical pathology practice. Previous case reports suggest the possibility of nephrogenic metaplasia progressing to clear cell adenocarcinoma, but a malignant potential of nephrogenic metaplasia is generally not acknowledged. A case of a 70-year-old female patient with multiple recurrences of ...

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