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Prognostic value of FHIT, CTNNB1, and MUC1 expression in non-small cell lung cancer

Woenckhaus, Matthias ; Merk, Johannes ; Stoehr, Robert ; Schaeper, Frank ; Gaumann, Andreas ; Wiebe, Karsten ; Hartmann, Arndt ; Hofstaedter, Ferdinand ; Dietmaier, Wolfgang



Abstract

Comprehensive expression analysis using microarrays has identified a number of differentially expressed genes in smoke-exposed bronchial epithelium and non-small cell lung cancers (NSCLCs). To evaluate the prognostic relevance of these proteins in NSCLCs, we used immunohistochemistry to investigate the expression of beta-catenin (CTNNB1), dickkopf, Xenopus, homolog of 3 (DKK3 gene), fibroblast ...

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