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Automated counting of labelled cells in rodent brain section images

Theis, Fabian J. ; Kohl, Z. ; Kuhn, H. ; Stockmeier, H. ; Lang, Elmar


Abstract

The genesis of new cells, especially of neurons, in the adult human brain is currently of great scientific interest. In order to measure neurogenesis in animals new born cells are labelled with specific markers such as BrdU; in brain sections these can later be analyzed and counted through the microscope. So far, the image analysis has been performed by hand. In this work, we present an algorithm ...

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