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Human monocyte chemotaxis: migrating cells are a subpopulation with multiple chemotaxin specificities on each cell.

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Falk, Werner ; Leonard, E.J.
Date of publication of this fulltext: 20 Jul 2010 05:07


Only 20 to 40% of human blood monocytes were capable of responding to chemotaxins in vitro. This limit is not due to restrictions of the in vitro system, but is due to the existence of a migrating subpopulation. Over a wide range, the number of cells migrating toward a given concentration of chemotaxin was directly proportional to the number added to the chemotaxis chamber. These monocytes ...


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