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Interferon-gamma is required in activation of macrophages for tumor cytotoxicity

URN to cite this document:
urn:nbn:de:bvb:355-epub-159727
DOI to cite this document:
10.5283/epub.15972
Männel, Daniela N. ; Falk, Werner
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Date of publication of this fulltext: 21 Jul 2010 05:06


Abstract

The participation of interferon-gamma in activation of murine macrophages for tumor cell lysis was investigated. Biochemically macrophage activation factor and interferon-gamma have not been separated. Antiviral titers correlated closely with macrophage activation in antigen- or mitogen-induced spleen cell supernatants. A monoclonal rat antibody that neutralized virus-induced interferon was also ...

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