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A new assay for interleukin-1 in the presence of interleukin-2

URN to cite this document:
urn:nbn:de:bvb:355-epub-159874
Falk, Werner ; Krammer, P.H. ; Männel, D.N.
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Date of publication of this fulltext: 21 Jul 2010 09:21


Abstract

A simple and reliable assay for interleukin-1 (IL-1) is described which has the advantage over other assays that it is independent of interleukin-2 (IL-2) production by the test cells. The assay makes possible the detection of IL-1 in the supernatants of T cell populations. The ability of IL-1 to induce IL-2 receptor expression in the absence of T cell mitogen is the basis of this assay. Thus, ...

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