A new assay for interleukin-1 in the presence of interleukin-2

URN to cite this document:: urn:nbn:de:bvb:355-epub-159874
DOI to cite this document:: 10.5283/epub.15987

Falk, Werner ; Krammer, P. H. ; Männel, D. N.

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Date of publication of this fulltext: 21 Jul 2010 09:21

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Abstract

A simple and reliable assay for interleukin-1 (IL-1) is described which has the advantage over other assays that it is independent of interleukin-2 (IL-2) production by the test cells. The assay makes possible the detection of IL-1 in the supernatants of T cell populations. The ability of IL-1 to induce IL-2 receptor expression in the absence of T cell mitogen is the basis of this assay. Thus, ...