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Monoclonal antibody-mediated tumor regression by induction of apoptosis

Trauth, B.C., Klas, C., Peters, A.M., Matzku, S., Möller, P., Falk, Werner, Debatin, K.M. and Krammer, P.H. (1989) Monoclonal antibody-mediated tumor regression by induction of apoptosis. Science (New York, N.Y.) 245 (4915), pp. 301-305.

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Date of publication of this fulltext: 08 Sep 2010 05:25

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Abstract

To characterize cell surface molecules involved in control of growth of malignant lymphocytes, monoclonal antibodies were raised against the human B lymphoblast cell line SKW6.4. One monoclonal antibody, anti-APO-1, reacted with a 52-kilodalton antigen (APO-1) on a set of activated human lymphocytes, on malignant human lymphocyte lines, and on some patient-derived leukemic cells. Nanogram ...

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Item type:Article
Date:1989
Institutions:Medicine > Lehrstuhl für Innere Medizin I
Identification Number:
ValueType
2787530PubMed ID
Classification:
NotationType
AnimalsMESH
Antibodies, Monoclonal/therapeutic useMESH
Antigens, Neoplasm/immunologyMESH
AutoradiographyMESH
B-Lymphocytes/immunologyMESH
Burkitt Lymphoma/therapyMESH
Cell SurvivalMESH
Cells, CulturedMESH
Electrophoresis, Polyacrylamide GelMESH
HumansMESH
Leukemia, B-Cell/therapyMESH
MiceMESH
Mice, NudeMESH
Precipitin TestsMESH
Remission InductionMESH
T-Lymphocytes/immunologyMESH
Tumor Cells, CulturedMESH
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:16007
Owner only: item control page

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