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High protein mobility in skinned rabbit muscle fibres observed by ¹H NMR spectroscopy

Kalbitzer, Hans Robert ; Schrumpf, M. ; Wray, J.


1H NMR spectra of skinned rabbit muscle fibers show a group of relatively sharp resonance lines which presumably originate from highly mobile protein domains. Comparison with the spectrum of myosin subfragment 1 suggests that these signals may come at least partly from mobile regions of the myosin head. NMR could possibly be used to characterize the movements of crossbridges in force generation.

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