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Bornyl cinnamate derivatives with antiinflammatory activity from Verbesina turbacensis

Lobitz, G. O. ; Heilmann, Jörg ; Zschocke, S. ; Tamayo-Castillo, G. ; Bauer, R. ; Merfort, I.



Abstract

From the lipophilic ext. of Verbesina turbacensis (-)-bornyl caffeate (I), (-)-bornyl ferulate (II), (-)-bornyl p-coumarate (III), and (-)-bornyl cis-4-hydroxy-cinnamate were isolated. The structures were established from spectral (UV, MS, 1H and 13C NMR) and polarimetric data. Compds. I-III were studied for their antiinflammatory activity using the 5-lipoxygenase assay. It could be shown that ...

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