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Cytotoxic cardenolides and antibacterial terpenoids from Crossopetalum gaumeri

Ankli, A. ; Heilmann, Jörg ; Heinrich, M. ; Sticher, O.



Abstract

From the methanol ext. of the roots of Crossopetalum gaumeri, four new highly cytotoxic cardenolides, securigenin-3beta -O-beta -6-deoxyguloside, 19-hydroxy-sarmentogenin-3beta -O-beta -6-deoxyguloside, sarmentogenin-3beta -O-[alpha -allosyl-(1-> 4)-beta -6-deoxyalloside], and securigenin-3beta -O-[alpha -allosyl-(1->4)-beta -6-deoxyalloside] were isolated. The dichloromethane ext. afforded the ...

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