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Radical scavenger activity of phenylethanoid glycosides in FMLP stimulated human polymorphonuclear leukocytes: structure-activity relationships

Heilmann, Jörg, Calis, I., Kirmizibekmez, H., Schuhly, W., Harput, S. and Sticher, O. (2000) Radical scavenger activity of phenylethanoid glycosides in FMLP stimulated human polymorphonuclear leukocytes: structure-activity relationships. Planta medica 66 (8), pp. 746-748.

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Abstract

Radical scavenger activities of 21 phenylethanoid glycosides, including 15 ester derivatives of caffeic, ferulic, vanillic and syringic acid as well as 6 deacyl derivatives were determined by quantifying their effects on the production of reactive oxygen species (ROS) in a luminol-enhanced chemiluminescence assay with formyl-methionyl-leucyl-phenylalanine (FMLP) stimulated human polymorphonuclear ...

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Item type:Article
Date:2000
Additional Information (public):Germany: Germany, Federal Republic of 59880-97-6 (N-Formylmethionine Leucyl-Phenylalanine)
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical Biology (Prof. Heilmann)
Identification Number:
ValueType
2001211559Other
Keywords:Free Radical Scavengers: CH, chemistry *Free Radical Scavengers: PD, pharmacology *Glycosides: PD, pharmacology Humans *N-Formylmethionine Leucyl-Phenylalanine: PD, pharmacology *Neutrophils: DE, drug effects Neutrophils: ME, metabolism Structure-Activity Relationship 0 (Free Radical Scavengers) 0 (Glycosides)
Dewey Decimal Classification:500 Science > 570 Life sciences
500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:No
Item ID:17183
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