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New Antibacterial Metabolites from the Cyanobacterium Nostoc commune (EAWAG 122b)

Jaki, B., Heilmann, Jörg und Sticher, O. (2000) New Antibacterial Metabolites from the Cyanobacterium Nostoc commune (EAWAG 122b). Journal of Natural Products 63 (9), S. 1283-1285.

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Zusammenfassung

Two new compds., a diterpenoid (I) and an anthraquinone (II), as well as an indane deriv. (III), which is reported as a natural product for the first time, have been isolated from the cells of the cultured cyanobacterium Nostoc commune (EAWAG 122b) by means of bioguided isolation. The structures were detd. by spectroscopic methods, mainly NMR, IR spectroscopy, and mass spectrometry. All isolates exhibit antibacterial activity.


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Dokumentenart:Artikel
Datum:2000
Zusätzliche Informationen (Öffentlich):CAN 133:263614 10-1 Microbial, Algal, and Fungal Biochemistry 22242-84-8P; 298183-91-2P (8-[(5-Carboxy-2,9-epoxy)benzyl]-2,5-dihydroxy-1,1,4a,7,8-pentamethyl-1,2,3,4,4a,6,7,8,9,10,10a-dodecahydrophenanthrene); 298183-92-3P (1,8-Dihydroxy-4-methylanthraquinone) Role: BAC (Biological activity or effector, except adverse), BOC (Biological occurrence), BSU (Biological study, unclassified), PRP (Properties), PUR (Purification or recovery), BIOL (Biological study), OCCU (Occurrence), PREP (Preparation) (isolation, structure and antibacterial activity of metabolites from the Cyanobacterium Nostoc commune (EAWAG 122b)
Institutionen:Chemie und Pharmazie > Institut für Pharmazie > Lehrstuhl Pharmazeutische Biologie (Prof. Heilmann)
Identifikationsnummer:
WertTyp
2000:519126Andere
Stichwörter / Keywords:Molecular structure determination methods (NMR spectrometric isolation, structure and antibacterial activity of metabolites from the Cyanobacterium Nostoc commune (EAWAG 122b) Antibacterial agents IR spectra Mass spectra Nostoc commune (isolation, structure and antibacterial activity of metabolites from the Cyanobacterium Nostoc commune (EAWAG 122b) Diterpenes Role: BAC (Biological activity or effector, except adverse), BOC (Biological occurrence), BSU (Biological study, unclassified), PRP (Properties), PUR (Purification or recovery), BIOL (Biological study), OCCU (Occurrence), PREP (Preparation) ( diterpenoid anthraquinone indane isolation structure Nostoc commune NMR IR mass spectra antibacterial
Dewey-Dezimal-Klassifikation:500 Naturwissenschaften und Mathematik > 570 Biowissenschaften, Biologie
500 Naturwissenschaften und Mathematik > 540 Chemie
Status:Veröffentlicht
Begutachtet:Ja, diese Version wurde begutachtet
An der Universität Regensburg entstanden:Nein
Eingebracht am:18 Okt 2010 10:27
Zuletzt geändert:24 Mai 2018 12:16
Dokumenten-ID:17185
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