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Novel extracellular diterpenoids with biological activity from the cyanobacterium Nostoc commune

Jaki, B., Orjala, J., Heilmann, Jörg, Linden, A., Vogler, B. und Sticher, O. (2000) Novel extracellular diterpenoids with biological activity from the cyanobacterium Nostoc commune. Journal of natural products 63 (3), S. 339-343.

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Zusammenfassung

Five novel extracellular metabolites with an unprecedented diterpenoid skeleton and designated comnostins A-D (I-IV, resp.) and E have been isolated from the culture medium of the terrestrial cyanobacterium Nostoc commune by means of bioguided isolation. The structures were detd. by spectroscopic methods, mainly NMR and mass spectrometry. The relative stereochem. of I was confirmed by ...

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Dokumentenart:Artikel
Datum:2000
Zusätzliche Informationen (Öffentlich):CAN 132:276414 10-1 Microbial, Algal, and Fungal Biochemistry 263842-17-7P (Comnostin B) Role: AGR (Agricultural use), BAC (Biological activity or effector, except adverse), BOC (Biological occurrence), BSU (Biological study, unclassified), PRP (Properties), PUR (Purification or recovery), THU (Therapeutic use), BIOL (Biological study), OCCU (Occurrence), PREP (Preparation), USES (Uses) (novel extracellular diterpenoids with biol. activity from the cyanobacterium Nostoc commune); 263842-16-6P (Comnostin A); 263842-18-8P (Comnostin C); 263842-19-9P (Comnostin D); 263842-20-2P (Comnostin E) Role: BAC (Biological activity or effector, except adverse), BOC (Biological occurrence), BSU (Biological study, unclassified), PRP (Properties), PUR (Purification or recovery), THU (Therapeutic use), BIOL (Biological study), OCCU (Occurrence), PREP (Preparation), USES (Uses) (novel extracellular diterpenoids with biol. activity from the cyanobacterium Nostoc commune)
Institutionen:Chemie und Pharmazie > Institut für Pharmazie > Lehrstuhl Pharmazeutische Biologie (Prof. Heilmann)
Identifikationsnummer:
WertTyp
2000:111827Andere
Stichwörter / Keywords:Animal cell line (Caco-2 cytotoxic and molluscicidal activities of comnostin B from Nostoc commune) Animal cell line (KB cytotoxic and molluscicidal activities of comnostin B from Nostoc commune) Antitumor agents (carcinoma cytotoxic and molluscicidal activities of comnostin B from Nostoc commune) New natural products (comnostins A-E (diterpenoids) Biomphalaria glabrata Molluscicides (cytotoxic and molluscicidal activities of comnostin B from Nostoc commune) Antibiotics Configuration (novel extracellular diterpenoids with biol. activity from the cyanobacterium Nostoc commune) Diterpenes Role: BAC (Biological activity or effector, except adverse), BOC (Biological occurrence), BSU (Biological study, unclassified), PRP (Properties), PUR (Purification or recovery), THU (Therapeutic use), BIOL (Biological study), OCCU (Occurrence Crystal structure (of comnostin A) Molecular structure (of comnostins A-E (diterpenoids) cyanobacteria bioactive diterpenoid comnostin bioactive diterpenoid Nostoc antibiotic comnostin Nostoc molluscicide comnostin B Nostoc cytotoxicity comnostin B Nostoc crystal structure comnostin A
Dewey-Dezimal-Klassifikation:500 Naturwissenschaften und Mathematik > 570 Biowissenschaften, Biologie
500 Naturwissenschaften und Mathematik > 540 Chemie
Status:Veröffentlicht
Begutachtet:Ja, diese Version wurde begutachtet
An der Universität Regensburg entstanden:Nein
Eingebracht am:18 Okt 2010 10:30
Zuletzt geändert:24 Mai 2018 12:16
Dokumenten-ID:17186
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