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New Phloroglucinol Derivatives from Hypericum papuanum

Winkelmann, Karin, Heilmann, Jörg, Zerbe, Oliver, Rali, Topul and Sticher, Otto (2000) New Phloroglucinol Derivatives from Hypericum papuanum. Journal of natural products 63 (1), pp. 104-108.

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Abstract

Bioactivity-guided fractionation of the petroleum ether ext. of the aerial parts of Hypericum papuanum led to the isolation of five new tricyclic phloroglucinol derivs. On the basis of extensive 1D and 2D NMR expts. as well as MS studies, their structures were elucidated as the C-3 epimers of 8-hydroxy-4,4,7-trimethyl-9-(2-methylpropionyl)-3-(1-methylvinyl)-5beta ...

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Item type:Article
Date:2000
Additional Information (public):CAN 132:134789 11-1 Plant Biochemistry 256471-46-2P Role: BAC (Biological activity or effector, except adverse), BOC (Biological occurrence), BSU (Biological study, unclassified), PRP (Properties), PUR (Purification or recovery), BIOL (Biological study), OCCU (Occurrence), PREP (Preparation) (ialibinone A; phloroglucinol derivs. from Hypericum papuanum); 256471-47-3P Role: BAC (Biological activity or effector, except adverse), BOC (Biological occurrence), BSU (Biological study, unclassified), PRP (Properties), PUR (Purification or recovery), BIOL (Biological study), OCCU (Occurrence), PREP (Preparation) (ialibinone B; phloroglucinol derivs. from Hypericum papuanum); 256471-48-4P Role: BAC (Biological activity or effector, except adverse), BOC (Biological occurrence), BSU (Biological study, unclassified), PRP (Properties), PUR (Purification or recovery), BIOL (Biological study), OCCU (Occurrence), PREP (Preparation) (ialibinone C; phloroglucinol derivs. from Hypericum papuanum); 256471-49-5P Role: BAC (Biological activity or effector, except adverse), BOC (Biological occurrence), BSU (Biological study, unclassified), PRP (Properties), PUR (Purification or recovery), BIOL (Biological study), OCCU (Occurrence), PREP (Preparation) (ialibinone D; phloroglucinol derivs. from Hypericum papuanum); 256471-50-8P Role: BAC (Biological activity or effector, except adverse), BOC (Biological occurrence), BSU (Biological study, unclassified), PRP (Properties), PUR (Purification or recovery), BIOL (Biological study), OCCU (Occurrence), PREP (Preparation) (ialibinone E; phloroglucinol derivs. from Hypericum papuanum)
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical Biology (Prof. Heilmann)
Identification Number:
ValueType
1999:784620Other
Keywords:Bacillus cereus Micrococcus luteus Staphylococcus epidermidis (antibacterial activity of phloroglucinol derivs. from Hypericum papuanum) Molecular structure (of ialibinone A phloroglucinol derivs. from Hypericum papuanum) Molecular structure (of ialibinone B phloroglucinol derivs. from Hypericum papuanum) Molecular structure (of ialibinone C phloroglucinol derivs. from Hypericum papuanum) Molecular structure (of ialibinone D phloroglucinol derivs. from Hypericum papuanum) Molecular structure (of ialibinone E phloroglucinol derivs. from Hypericum papuanum) Antibacterial agents New natural products St.-John's-wort (phloroglucinol derivs. from Hypericum papuanum) phloroglucinol deriv Hypericum
Dewey Decimal Classification:500 Science > 570 Life sciences
500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:No
Item ID:17190
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