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Antibacterial and cytotoxic activity of prenylated bicyclic acylphloroglucinol derivatives from Hypericum amblycalyx

Winkelmann, Karin ; San, Metin ; Kypriotakis, Zacharias ; Skaltsa, Helen ; Bosilij, Blazenka ; Heilmann, Jörg


Two new bicyclic acylphloroglucinol derivs., hypercalyxone A (I) and B (II), were isolated from the petroleum ether ext. of the aerial parts of H. amblycalyx, together with 2 further compds. (1-[5,7-dihydroxy-2-methyl-2-(4-methylpent-3-enyl)-chroman-8-yl]-2-methylpropan-1-one [III] and 1-[5,7-dihydroxy-2-methyl-2-(4-methylpent-3-enyl)-chroman-8-yl]-2-methylbutan-1-one [IV]), which have been ...


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