Go to content
UR Home

Design and synthesis of tacrine-ferulic acid hybrids as multi-potent anti-Alzheimer drug candidates

Fang, Lei ; Kraus, Birgit ; Lehmann, Jochen ; Heilmann, Jörg ; Zhang, Yihua ; Decker, Michael


Five tacrine-ferulic acid hybrids were designed and synthesized as multi-potent anti-Alzheimer drug candidates. All target compds. have better acetylcholinesterase inhibitory activity and comparable butyrylcholinesterase inhibitory activity in relation to tacrine. Interestingly, I showed a reversible and non-competitive inhibitory action for acetylcholinesterase indicating interaction with the ...


Owner only: item control page
  1. Homepage UR

University Library

Publication Server


Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: daten@ur.de
0941 943 -5707

Contact persons