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Synthesis, Cytotoxicity, and Antioxidative Activity of Minor Prenylated Chalcones from Humulus lupulus

Vogel, Susanne und Heilmann, Jörg (2008) Synthesis, Cytotoxicity, and Antioxidative Activity of Minor Prenylated Chalcones from Humulus lupulus. Journal of natural products 71 (7), S. 1237-1241.

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Zusammenfassung

The minor hop (Humulus lupulus) chalcones 3'-geranylchalconaringenin (3), 5'-prenylxanthohumol (4), flavokawin (5), xanthohumol H (8), xanthohumol C (9), and 1'',2''-dihydroxanthohumol C (10) were synthesized. The non-natural chalcones 3'-geranyl-6'-O-methylchalconaringenin (2), 3'-methylflavokawin (6), and 2'-O-methyl-3'-prenylchalconaringenin (7) were also synthesized. Cytotoxicity was ...

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Dokumentenart:Artikel
Datum:2008
Zusätzliche Informationen (Öffentlich):CAN 149:246662 30-10 Terpenes and Terpenoids 6754-58-1 Role: PAC (Pharmacological activity), BIOL (Biological study) (prepn. of prenylated/geranylated chalcones from Humulus lupulus, and study of their antioxidative activity and cytotoxicity in HeLa cells); 37308-75-1P; 189299-03-4P; 189299-04-5P; 189299-05-6P (Xanthohumol C); 250603-94-2P; 688359-98-0P (Xanthohumol H); 1044743-34-1P; 1044743-35-2P; 1044743-36-3P Role: PAC (Pharmacological activity), SPN (Synthetic preparation), BIOL (Biological study), PREP (Preparation) (prepn. of prenylated/geranylated chalcones from Humulus lupulus, and study of their antioxidative activity and cytotoxicity in HeLa cells); 123-08-0 (4-Hydroxybenzaldehyde); 480-66-0; 870-63-3 (Prenyl bromide); 6138-90-5 (Geranyl bromide) Role: RCT (Reactant), RACT (Reactant or reagent) (prepn. of prenylated/geranylated chalcones from Humulus lupulus, and study of their antioxidative activity and cytotoxicity in HeLa cells); 90-24-4P; 6515-21-5P; 23121-32-6P (2-Hydroxy-4,6-dimethoxy-3-methylacetophenone); 25983-76-0P; 27364-71-2P; 30403-01-1P; 32550-59-7P; 65490-09-7P; 84092-45-5P; 90632-20-5P; 160624-22-6P; 450336-12-6P; 955950-40-0P; 1044743-37-4P; 1044743-38-5P; 1044743-39-6P; 1044743-40-9P; 1044743-41-0P; 1044743-42-1P; 1044743-43-2P; 1044743-44-3P; 1075728-02-7P; 1173195-54-4P; 1173196-14-9P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (prepn. of prenylated/geranylated chalcones from Humulus lupulus, and study of their antioxidative activity and cytotoxicity in HeLa cells)
Institutionen:Chemie und Pharmazie > Institut für Pharmazie > Lehrstuhl Pharmazeutische Biologie (Prof. Heilmann)
Identifikationsnummer:
WertTyp
2008:823843Andere
Stichwörter / Keywords:Antioxidants (phenolic prepn. of prenylated/geranylated chalcones from Humulus lupulus, and study of their antioxidative activity and cytotoxicity in HeLa cells) Terpenes Role: PAC (Pharmacological activity), SPN (Synthetic preparation), BIOL (Biological study), PREP (Preparation) (phenolic prepn. of prenylated/geranylated chalcones from Humulus lupulus, and study of their antioxidative activity and cytotoxicity in HeLa cells) Antitumor agents Neoplasm (prepn. of prenylated/geranylated chalcones from Humulus lupulus, and study of their antioxidative activity and cytotoxicity in HeLa cells) Chalcones Role: PAC (Pharmacological activity), SPN (Synthetic preparation), BIOL (Biological study), PREP (Preparation) (prepn. of prenylated/geranylated chalcones from Humulus lupulus, and study of their antioxidative activity and cytotoxicity in HeLa Phenols Role: PAC (Pharmacological activity), SPN (Synthetic preparation), BIOL (Biological study), PREP (Preparation) (terpenoid prepn. of prenylated/geranylated chalcones from Humulus lupulus, and study of their antioxidative activity and cytotoxicity in HeLa cells) prenylated geranylated Humulus lupulus chalcone prepn antitumor antioxidative activity
Dewey-Dezimal-Klassifikation:500 Naturwissenschaften und Mathematik > 570 Biowissenschaften, Biologie
500 Naturwissenschaften und Mathematik > 540 Chemie
Status:Veröffentlicht
Begutachtet:Ja, diese Version wurde begutachtet
An der Universität Regensburg entstanden:Ja
Eingebracht am:18 Okt 2010 13:48
Zuletzt geändert:24 Mai 2018 12:16
Dokumenten-ID:17242
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