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Effects of new anti-estrogens on serially transplanted human breast carcinomas in nude mice

Michel, R. T. ; Schönenberger, Helmut Bastert, Gunther , eds.



Abstract

The effects of the estrogen 4,4'-DES-epoxide and the antistrogens, 3,3'-DES-epoxide, 3,3'-dihydroxy-alpha ,beta -diethylstilbene, and 3,4-di(hydroxyphenyl)hexane, were studied on estrogen and progesterone-contg. pre- and postmenopausal serially transplanted human breast tumors in nude mice. Treatment of premenopausal tumors with the 4 steroids or ovariectomy plus aminoglutethimide plus tamoxifen ...

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