Preparation of 1,1,2,2-tetramethyl-1,2-bis(2-fluoro-4-hydroxyphenyl)ethane derivatives and antitumor pharmaceuticals containing them
Schönenberger, Helmut, Hartmann, Rolf, Schneider, Martin, Schwarz, Walter und Engel, Juergen (1986) Preparation of 1,1,2,2-tetramethyl-1,2-bis(2-fluoro-4-hydroxyphenyl)ethane derivatives and antitumor pharmaceuticals containing them.Veröffentlichungsdatum dieses Volltextes: 15 Nov 2010 14:58
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| Dokumentenart | Patent | ||||||
| Seitenanzahl: | 25 | ||||||
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| Datum | 1986 | ||||||
| Zusätzliche Informationen (Öffentlich) | CAN 107:121081 63-6 Pharmaceuticals Patent 19861211 74457-86-6 (2-Fluoro-4-methoxyacetophenone) Role: RCT (Reactant), RACT (Reactant or reagent) (Grignard reaction of, with Me iodide); 4124-30-5 (Dichloroacetic anhydride) Role: RCT (Reactant), RACT (Reactant or reagent) (esterification by, of bis(fluorohydroxyphenyl)tetramethylethane); 96826-32-3P Role: RCT (Reactant), PREP (Preparation), RACT (Reactant or reagent) (prepn. and de-O-methylation of); 96826-25-4P (2-(2-Fluoro-4-methoxyphenyl)-2-propanol) Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (prepn. and reductive coupling of); 96826-17-4P; 110300-86-2P; 110300-87-3P; 110300-88-4P; 110300-89-5P Role: THU (Therapeutic use), BIOL (Biological study), PREP (Preparation), USES (Uses) (prepn. of, as neoplasm inhibitor); 506-68-3 (Bromocyan) Role: RCT (Reactant), RACT (Reactant or reagent) (reaction of, with bis(fluorohydroxyphenyl)tetramethylethane) A1 DE 85-3520622 19850608 | ||||||
| Institutionen | Chemie und Pharmazie > Institut für Pharmazie > Entpflichtete oder im Ruhestand befindliche Professoren > Prof. Schönenberger | ||||||
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| Stichwörter / Keywords | Neoplasm inhibitors (tetramethylbis(fluorohydroxyphenyl)ethane derivs., for estrogen receptor-pos. tumors) Prostate gland (disease, benign hyperplasia, treatment of, tetramethylbis(fluorohydroxyphenyl)ethane for) Mammary gland Prostate gland (neoplasm, treatment of, tetramethylbis(fluorohydroxyphenyl)ethane for) fluorohydroxyphenylethane prepn neoplasm inhibitor antiestrogen fluorohydroxyphenylethane estrogen inhibitor fluorohydroxyphenylethane | ||||||
| Dewey-Dezimal-Klassifikation | 500 Naturwissenschaften und Mathematik > 540 Chemie | ||||||
| Status | Veröffentlicht | ||||||
| Begutachtet | Ja, diese Version wurde begutachtet | ||||||
| An der Universität Regensburg entstanden | Ja | ||||||
| Dokumenten-ID | 17659 |
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