Go to content
UR Home

Investigations on the antiproliferative effects of amino acid antagonists targeting for aminoacyl-tRNA synthetases. Part II. The antileukemic effect

Laske, Reiner ; Schönenberger, Helmut ; Holler, Eggehard


Amino acid antagonists with proven or potential inhibitory activities on aminoacyl-tRNA synthetases were tested for their antiproliferative effect against the murine leukemic cell line P338D1. Micromolar concns. of the compds. S-tritylcysteine, fenitropan, and beta -chloroalanine were markedly inhibitory. In the mouse only S-tritylcysteine was effective against leukemia P388 (T/C = 211%). The ...


Owner only: item control page
  1. Homepage UR

University Library

Publication Server


Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons