Synthesis and antitumor activity of platinum(II) complexes containing substituted ethylenediamine ligands
Brunner, Henri, Hankofer, Peter, Holzinger, Ulrich, Treittinger, Barbara and Schönenberger, Helmut (1990) Synthesis and antitumor activity of platinum(II) complexes containing substituted ethylenediamine ligands. European journal of medicinal chemistry. 25 (1), pp. 35-44.Date of publication of this fulltext: 12 Nov 2010 07:24
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| Item type | Article | ||||
| Journal or Publication Title | European journal of medicinal chemistry. | ||||
| Publisher: | EDIFOR | ||||
|---|---|---|---|---|---|
| Volume: | 25 | ||||
| Number of Issue or Book Chapter: | 1 | ||||
| Page Range: | pp. 35-44 | ||||
| Date | 1990 | ||||
| Additional Information (public) | CAN 113:107966 78-7 Inorganic Chemicals and Reactions 51-31-0; 2627-86-3 Role: RCT (Reactant), RACT (Reactant or reagent) (amidation by, of benzyloxycarbonylphenylalanine); 3588-57-6 Role: RCT (Reactant), RACT (Reactant or reagent) (amidation of, with isopropylamine); 29622-19-3P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (prepn. and amidation of, followed by redn.); 105368-95-4P Role: SPN (Synthetic preparation), PREP (Preparation) (prepn. and anionic exchange and antitumor activity of racemic); 72426-83-6P; 102050-52-2P; 105237-00-1P; 105308-31-4P; 105856-64-2P; 105856-65-3P; 105870-24-4P; 128610-09-3P; 128610-10-6P; 128610-12-8P; 128610-14-0P; 128610-15-1P; 128610-16-2P; 128636-07-7P; 128636-08-8P; 128636-09-9P; 128636-10-2P; 128636-11-3P; 128636-13-5P; 128636-14-6P; 128658-76-4P; 128658-77-5P; 128705-27-1P Role: BAC (Biological activity or effector, except adverse), BSU (Biological study, unclassified), SPN (Synthetic preparation), THU (Therapeutic use), BIOL (Biological study), PREP (Preparation), USES (Uses) (prepn. and antitumor activity of); 105237-01-2P; 105237-02-3P; 105237-03-4P; 105237-04-5P; 105237-05-6P; 105856-39-1P; 105856-40-4P; 105856-49-3P; 105856-52-8P; 105856-54-0P; 105856-55-1P; 105856-56-2P; 105856-57-3P; 105856-58-4P; 105856-59-5P; 105856-61-9P; 105870-25-5P; 128594-51-4P; 128594-52-5P; 128594-53-6P; 128594-54-7P; 128594-55-8P; 128594-56-9P; 128594-57-0P; 128594-58-1P; 128594-59-2P; 128594-60-5P; 128594-61-6P; 128594-62-7P; 128594-63-8P; 128594-69-4P; 128610-20-8P; 128610-21-9P; 128610-23-1P; 128610-24-2P; 128610-25-3P; 128636-06-6P; 128705-23-7P; 128705-24-8P; 128705-25-9P; 128705-26-0P; 128705-28-2P; 128705-29-3P Role: SPN (Synthetic preparation), PREP (Preparation) (prepn. and antitumor activity of racemic); 104907-23-5P Role: SPN (Synthetic preparation), PREP (Preparation) (prepn. and cleavage of); 3321-96-8P; 4441-50-3P; 14108-60-2P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (prepn. and esterification of, followed by amidation and redn.); 51-65-0P; 63-91-2P (L-Phenylalanine); 456-88-2P; 673-06-3P (D-Phenylalanine); 1956-15-6P; 2629-55-2P; 2835-06-5P; 4599-47-7P; 5472-67-3P; 5472-68-4P; 5472-70-8P; 7635-29-2P; 14091-08-8P; 14091-11-3P; 14091-16-8P; 14173-39-8P; 21176-60-3P; 23633-07-0P; 28095-56-9P; 32133-35-0P; 32133-36-1P; 33522-63-3P; 34993-02-7P; 76985-08-5P; 80997-87-1P; 94294-08-3P; 108540-72-3P; 128833-94-3P; 128833-95-4P; 128833-96-5P; 128833-97-6P; 128833-98-7P; 128833-99-8P; 128834-00-4P; 128834-01-5P; 128834-02-6P; 128834-03-7P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (prepn. and esterification of, followed by amidation and redn. of); 75543-73-6P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (prepn. and reaction of, with acetone); 128834-07-1P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (prepn. and reaction with hydrogen bromide and redn. of); 55857-61-9P; 60058-40-4P; 68319-33-5P; 81375-37-3P; 108945-12-6P; 128834-04-8P; 128834-05-9P; 128834-06-0P; 128834-08-2P; 128834-09-3P; 128834-10-6P; 128834-11-7P; 128834-12-8P; 128900-00-5P; 128900-01-6P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (prepn. and redn. of); 29802-24-2P; 85612-59-5P; 85612-60-8P; 104907-19-9P; 104907-20-2P; 104907-21-3P; 104907-22-4P; 104936-00-7P; 104975-45-3P; 105237-15-8P; 105469-09-8P; 125293-80-3P; 128636-12-4P; 128833-58-9P; 128833-59-0P; 128833-60-3P; 128833-61-4P; 128833-62-5P; 128833-64-7P; 128833-65-8P; 128833-66-9P; 128833-67-0P; 128833-68-1P; 128833-69-2P; 128833-70-5P; 128833-71-6P; 128833-72-7P; 128833-73-8P; 128833-74-9P; 128833-75-0P; 128833-76-1P; 128833-77-2P; 128833-78-3P; 128833-79-4P; 128833-80-7P; 128833-81-8P; 128833-82-9P; 128833-83-0P; 128833-84-1P; 128833-85-2P; 128833-86-3P; 128833-87-4P; 128833-89-6P; 128833-90-9P; 128833-91-0P; 128833-92-1P; 128833-93-2P; 28834-13-9P; 128834-14-0P; 128899-90-1P; 128899-91-2P; 128899-92-3P; 128899-93-4P; 128899-94-5P; 128899-95-6P; 128899-96-7P; 128899-97-8P; 128899-98-9P; 128899-99-0P; 128900-02-7P; 128900-03-8P; 176910-85-3P Role: SPN (Synthetic preparation), PREP (Preparation) (prepn. of); 128610-22-0P Role: SPN (Synthetic preparation), PREP (Preparation) (prepn. of reacmic); 74-89-5 (Methanamine) Role: RCT (Reactant), RACT (Reactant or reagent) (reaction of, with Me phenylalanine); 17193-31-6 Role: RCT (Reactant), RACT (Reactant or reagent) (reaction of, with formic acid and formaldehyde or acetone); 2577-90-4 Role: RCT (Reactant), RACT (Reactant or reagent) (reaction of, with methylamine); 10025-99-7 (Potassium tetrachloroplatinate(2-) Role: RCT (Reactant), RACT (Reactant or reagent) (reaction of, with substituted ethylenediamine); 75768-06-8 Role: RCT (Reactant), RACT (Reactant or reagent) (reaction with hydrogen bromide and redn. of) | ||||
| Institutions | Chemistry and Pharmacy > Institute of Pharmacy > Alumni or Retired Professors > Prof. Schönenberger | ||||
| Identification Number |
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| Keywords | Neoplasm inhibitors (platinate chloro substituted-ethylendiamine complexes) Amino acids Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (prepn. and esterification of, followed by amidation and redn.) platinate chloro substituted ethylenediamine antitumor activity platinate chloro substituted ethylenediamine amino acid esterification amination amino acid ester amide prepn redn | ||||
| Dewey Decimal Classification | 500 Science > 540 Chemistry & allied sciences | ||||
| Status | Published | ||||
| Refereed | Yes, this version has been refereed | ||||
| Created at the University of Regensburg | Yes | ||||
| Item ID | 17679 |
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