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Mammary-tumor-inhibiting properties of (S,S)-[1,2-bis(4-hydroxyphenyl)ethylenediamine]dichloroplatinum(II)

Spruss, Thilo, Gust, Ronald, Müller, Richard, Engel, Juergen and Schönenberger, Helmut (1990) Mammary-tumor-inhibiting properties of (S,S)-[1,2-bis(4-hydroxyphenyl)ethylenediamine]dichloroplatinum(II). Archiv der Pharmazie 323 (2), pp. 99-102.

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[(S,S)-1,2-Bis(4-hydroxyphenyl)ethylenediamine]dichloroplatinum (II) [(S,S)-I shows a strong and dose-dependent effect on the hormone-dependent MXT mammary carcinoma of the mouse. R,R/S,S-I is markedly less active. Other I analogs were also tested.

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Item type:Article
Additional Information (public):CAN 112:191483 1-6 Pharmacology 7440-06-4D (Platinum); 91265-66-6; 91326-61-3; 91326-62-4; 105856-23-3; 111086-58-9; 126735-37-3 Role: BIOL (Biological study) (mammary carcinoma inhibition by, hormone dependence in)
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Alumni or Retired Professors > Prof. Schönenberger
Projects:SFB 234
Identification Number:
Keywords:Neoplasm inhibitors (carcinoma, [bis(hydroxyphenyl)ethylenediamine]dichloroplatinum(II) as, in mammary gland, hormone dependence in) Mammary gland (neoplasm, carcinoma, inhibition of, by [bis(hydroxyphenyl)ethylendiamine]dichloroplatinum(II), hormone dependence in) platinum complex mammary carcinoma inhibition hydroxyphenylethylenediaminedichloroplatinum mammary carcinoma inhibition
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:17685
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