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Synergistic bactericides

Schönenberger, Helmut, Von Angerer, Erwin, Meindl, Wolfgang Rudolf and Ruckdeschel, Gotthard (1985) Synergistic bactericides.

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Compns. contg. 4,4'-diaminodiphenyl sulfone, p-aminosalicylic acid, streptomycin, or rifampicin and a benzylamine I (R = H, alkyl; R1, R2 = H, F, Cl, Br) are synergistic bactericides against mycobacteria, such as those causing tuberculosis and leprosy. Thus, as shown by the fractional inhibitory concn. method, 4,4'-diaminodiphenyl sulfone and I-HCl (R = Me, R1 = R2 = Cl) were synergistic against Mycobacterium lufu on Dubos medium contg. 5% bovine albumin. I were prepd. by known methods.

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Item type:Patent
Additional Information (public):CAN 104:203794 10-5 Microbial Biochemistry Patent 19851212 54-85-3; 57-92-1; 65-49-6; 80-08-0; 738-70-5; 1627-73-2; 13292-46-1 Role: BIOL (Biological study) (bactericidal compn. contg. benzylamine and, synergistic, against mycobacteria); 100-82-3; 4152-90-3; 10269-01-9; 16183-35-0; 39180-82-0; 39190-98-2; 39191-07-6; 39989-43-0; 60509-34-4; 60509-39-9; 67344-77-8; 90389-22-3; 90389-85-8; 90389-86-9; 90389-88-1; 90389-90-5; 90389-91-6; 90389-92-7; 90390-25-3; 90390-27-5 Role: BIOL (Biological study) (bactericidal compn. contg., synergistic, against mycobacteria); 90390-48-0P Role: SPN (Synthetic preparation), PREP (Preparation) (prepn. and conversion of, to chlorofluorobenzyl alc.); 79944-63-1P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (prepn. and diazotization of); 90390-46-8P Role: RCT (Reactant), PREP (Preparation), RACT (Reactant or reagent) (prepn. and diazotization-chlorination of); 79944-64-2P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (prepn. and oxidn. of, to aldehyde); 79944-62-0P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (prepn. and redn. of); 90390-49-1P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (prepn. and reductive amination of); 90389-23-4P; 90389-24-5P; 90389-25-6P; 90389-29-0P; 90389-30-3P; 90389-31-4P; 90389-32-5P; 90389-33-6P; 90389-34-7P; 90389-35-8P; 90389-40-5P; 90389-73-4P; 90389-74-5P; 90389-75-6P; 90389-84-7P; 90390-21-9P; 90390-22-0P; 90390-23-1P; 90390-24-2P; 90390-28-6P; 90390-29-7P; 90390-30-0P; 90390-31-1P; 90390-32-2P; 90390-33-3P; 90390-34-4P; 90390-35-5P; 90390-36-6P; 90390-37-7P Role: PREP (Preparation) (prepn. of, as synergistic bactericide component, against mycobacteria); 71022-43-0 Role: RCT (Reactant), RACT (Reactant or reagent) (redn. of, selective) C1
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Alumni or Retired Professors > Prof. Schönenberger
Identification Number:
84-3423691 3423691Other
Keywords:Mycobacterium (control of, by benzylamine-contg. synergistic bactericidal compns.) Leprosy Tuberculosis (treatment of, benzylamine-contg. synergistic bactericides for) Bactericides, Disinfectants, and Antiseptics (synergistic, benzylamine-contg. compns., against mycobacteria) Mycobacterium bactericide synergism benzylamine
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:18060
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