Go to content
UR Home

Preparation of aminoplatinum phenylindole antitumor agents

Von Angerer, Erwin, Knebel, Norbert, Schönenberger, Helmut and Engel, Juergen (1988) Preparation of aminoplatinum phenylindole antitumor agents.

Full text not available from this repository.


Title compds. I (X = physiolog. acceptable anion; R1 = H, OH, C2-6 alkamoyloxy; R2 = H, halo; R3 = H, C1-6 alkyl; R4 = OH, C2-6 alkamoyloxy; R5, R6 = H, halo; Alk = C2-10 alkylene with 1,4-phenylene optionally in chain; A-B = alkylenediamine, etc.) are prepd. as antitumor agents. Reaction of 1.01 mmol each of II and K2PtCl4 in DMF/H2O at 40 Deg for 24 with exclusion of light gave III. I showed ...


Export bibliographical data

Item type:Patent
Additional Information (public):CAN 109:47368 78-7 Inorganic Chemicals and Reactions Patent 19880406 91444-18-7 Role: RCT (Reactant), RACT (Reactant or reagent) (alkylation of); 629-03-8 (1,6-Dibromohexane) Role: RCT (Reactant), RACT (Reactant or reagent) (alkylation of phenylindole deriv. by); 115140-97-1P; 115140-98-2P; 115140-99-3P; 115141-00-9P; 115141-01-0P; 115141-02-1P; 115160-74-2P; 115160-75-3P; 115357-82-9P; 115357-83-0P; 115357-84-1P; 115357-85-2P; 115357-86-3P; 115357-87-4P; 115357-88-5P; 115357-89-6P; 115357-90-9P; 115362-88-4P; 115378-88-6P Role: SPN (Synthetic preparation), PREP (Preparation) (prepn. of, as antitumor agent); 115084-37-2P; 115084-38-3P; 115084-40-7P Role: SPN (Synthetic preparation), PREP (Preparation) (prepn. of, as intermediate for phenylindolealkyleneamino ligand); 115084-39-4P; 115084-41-8P; 115084-42-9P; 115084-43-0P Role: SPN (Synthetic preparation), PREP (Preparation) (prepn. of, as ligand for aminoplatinum antitumor agent); 1121-60-4 (2-Pyridinealdehyde) Role: RCT (Reactant), RACT (Reactant or reagent) (reaction of, with aminohexylphenylindole deriv.); 107-15-3 (1,2-Ethanediamine) Role: RCT (Reactant), RACT (Reactant or reagent) (reaction of, with methoxyphenylindole deriv.) Designated States R: AT, BE, CH, DE, ES, FR, GB, GR, IT, LI, LU, NL, SE. A2 DE 86-3633673 19861003
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Alumni or Retired Professors > Prof. Schönenberger
Projects:SFB 234
Identification Number:
87-113384 262498Other
Keywords:Neoplasm inhibitors (platinum phenylindolealkyleneamino complexes) platinum phenylindolealkyleneamine complex prepn antitumor
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:18063
Owner only: item control page
  1. Homepage UR

University Library

Publication Server


Publishing: oa@ur.de

Dissertations: dissertationen@ur.de

Research data: daten@ur.de

Contact persons