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The action of aminomethylating carcinostatics on experimental tumors. IV. Cytostatic agents

Schönenberger, Helmut ; Adam, A. ; Adam, D.


The carcinostatic effects of 24 aminomethylating compds. were tested against Ehrlich ascites carcinoma and sarcoma 180 in mice and against Yoshida sarcoma in rats. Intraperitoneal injections of N,N'-dimethyl-N,N'-diethylthiomethylethylenediamine dihydrochloride (3400 mg./kg.), N,N'-diethylthiomethylimidazolidine dihydrochloride (2500 mg./kg.), 1,4,6,9-tetraazatricyclo[,4]dodecane (575 ...


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