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Cytostatic agents. 9. Relations between physicochemical properties and antimicrobial activity of beta -amino ketones

Schönenberger, Helmut ; Bastug, T.


The relation between antibacterial and antifungal activities of 6 aliphatic beta -amino ketones, 5 alpha -phenyl-beta -amino ketones, 8 beta -amino propiophenones, and 9 alpha -phenyl-beta -amino propiophenones and partition coeff., H2O soly. of the base, and total soly. was studied. The bacteriostatic effect of all investigated beta -amino ketones was small, but the fungistatic effect, with the ...


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