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Action mechanism of antimicrobial beta -amino ketones

Schönenberger, Helmut ; Bastug, T. ; Bindl, L. ; Adam, Adelheid ; Adam, Dieter ; Petter, A. ; Zwez, W.


Structure-activity relations of aliphatic beta -aminoketones, beta -aminopropiophenones, alpha -phenyl-beta -aminoketones, and alpha -phenyl-beta -aminopropiophenones against fungis, yeasts, and gram-pos., and gram-neg. bacteria showed that the fungicidal activity was due to the beta -amino ketone structure. Substitution of a Ph group on either the alpha -C or carbonyl C increased fungicidal ...


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