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Effect of meso- and dl-N,N'-dibutyl-alpha,alpha-bis(3-chloro-4-methoxyphenyl)ethylenediamine on the mammary tumor in the Sprague-Dawley rat induced by 7,12-dimethylbenz[alpha]anthracene (DMBA). 14. Cytostatic compounds

Schönenberger, Helmut ; Griebl, G. ; Adam, D. ; Adam, A.


Following the production of meso-N,N'-dibutyl-alpha ,alpha '-bis(3-chloro-4-methoxyphenyl)ethylenediamine (I) [34608-86-1] and dl-N,N'-dibutyl-alpha ,alpha '-bis(3-chloro-4-methoxyphenyl)ethylenediamine (II) [27958-22-1] by the redn. of 3-chloro-4-methoxybenzylidenebutylamine with activated Al in alc., the compds. were tested for antimicrobial and antitumor activity. II inhibited ...


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