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Cytostatics 11. Comparative study on the antimicrobial action of tertiary and quaternary beta-aminoketones

Schönenberger, Helmut ; Lippert, P.



Abstract

Fungistatic and bacteriostatic activities of some tertiary and quaternary beta -aminoketones were tested against a variety of microorganisms. Greatest activities (relative to that of formaldehyde) were obsd. for 1-dimethylamino-2-phenylbutan-3-one (I), 2-phenyl-3-dimethylaminopropiophenone (II), and their quaternary salts formed with methyl iodide. Quaternization of the beta -aminoketones ...

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