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Cytostatics. 18. Carcinostatic and antimicrobial activity of acylated N-hemiacetals, aminals, and aminomethyl esters of dithiocarbamic acid

Schönenberger, Helmut ; Lippert, P.



Abstract

Twenty-four title compds., RCONR1CH2R2 (I, R = Me, Ph, 3- or 4-pyridyl; R1 = H or RR1 = CH2CH2CO; R2 = OH, NMe2, S2CNMe2, NEt2, S2CNEt2, morpholino, morpholinothiocarbonylthio, 4-methyl-1-piperazinyl, and 4-methyl-1-piperazinylthiocarbonylthio), prepd. by known methods from RCONHR1 with HCHO and (or) amine and (or) CS2, showed in vivo carcinostatic and in vitro fungistatic effects, whereas they ...

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