Studies on the mechanisms of action of local anesthetics. Part 9. N-Aminoacyl-beta -phenylalkylamine studies for the development of antidepressants from psychostimulants

Schönenberger, Helmut, Petter, A., Beck, D., Endres, W. und Servatius, H. J. (1976) Studies on the mechanisms of action of local anesthetics. Part 9. N-Aminoacyl-beta -phenylalkylamine studies for the development of antidepressants from psychostimulants. Pharmazie 31 (12), S. 882-886.

Im Publikationsserver gibt es leider keinen Volltext zu diesem Eintrag.

Zusammenfassung

Of 10 N-L-phenylalanyl-beta -phenylalkylamines[PhCH2CH(NH2)CONR3CHR2CHR1Ph] (I, R1 = H or OH; R2 and R3 = H or Me) prepd. and tested as antidepressants, I(R1 = H; R2 and R3 = Me) [61925-95-9] and I(R1 = OH; R2 = Me; R3 = H) (II) [61950-64-9] were the most active compds. in the inhibition of cond. in strips of frog heart ventrical, I(R1 and R3 = H; R2 = Me) (III) [61925-94-8] and II were the most ...

Bibliographische Daten exportieren