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Synthesis and testing the cardiocirculatory effects of N-(3'-methoxybenzamidomethyl)-D-norephedrine and analogous compounds

Schönenberger, Helmut, Petter, Alfred, Kuehling, Volker and Bindl, Ludwig (1976) Synthesis and testing the cardiocirculatory effects of N-(3'-methoxybenzamidomethyl)-D-norephedrine and analogous compounds. Archiv der Pharmazie 309 (4), pp. 289-301.

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Twenty-six substituted N-benzamidomethyl and 3 N-(diphenylacetamido)methyl amines were prepd. by coupling I groups (R1 = H or MeO; R2 = H, Me MeO, EtO, PrO, or Cl; R3 = H, MeO, or Cl) and Ph2CHCONHCH2 groups, resp., to the N atom of phenylethylamine, amphetamine, phenylethanolamine, norephedrine, ephedrine, norfenefrine, and noradrenaline. Tests on the isolated guinea pig heart showed that the ...


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Item type:Article
Additional Information (public):CAN 85:40643 1-3 Pharmacodynamics 15687-41-9 Role: BAC (Biological activity or effector, except adverse), BSU (Biological study, unclassified), BIOL (Biological study) (cardiovascular activity of, norephedrine analogs in relation to); 59630-56-7P; 59630-57-8P; 59630-58-9P; 59630-59-0P; 59630-60-3P; 59630-61-4P; 59630-62-5P; 59630-63-6P; 59630-64-7P; 59630-65-8P; 59630-66-9P; 59630-67-0P; 59630-68-1P; 59630-69-2P; 59630-70-5P; 59630-71-6P; 59630-72-7P; 59630-73-8P; 59630-74-9P; 59630-75-0P; 59630-76-1P; 59630-77-2P; 59630-78-3P; 59630-79-4P; 59630-80-7P; 59630-81-8P; 59630-82-9P; 59643-15-1P; 59643-16-2P Role: SPN (Synthetic preparation), PREP (Preparation) (prepn. and cardiovascular activity of); 6282-02-6P; 13855-74-8P; 40478-07-7P; 57428-72-5P; 59630-85-2P; 59630-86-3P; 59630-87-4P; 59630-88-5P; 59630-89-6P; 59630-90-9P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (prepn. and chlorination of); 59630-83-0P; 59630-84-1P Role: SPN (Synthetic preparation), PREP (Preparation) (prepn. of)
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Alumni or Retired Professors > Prof. Schönenberger
Identification Number:
Keywords:Circulation Heart ((methoxybenzamidomethyl)norephedrine and related compds. effect on) cardiovascular catechol amine deriv heart catechol amine deriv circulation catechol amine deriv blood pressure catechol amine deriv norephedrine analog heart circulation
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:18172
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