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CRX ChIP-seq reveals the cis-regulatory architecture of mouse photoreceptors.

Corbo, Joseph C, Lawrence, Karen A, Karlstetter, Marcus, Myers, Connie A, Abdelaziz, Musa, Dirkes, William, Weigelt, Karin, Seifert, Martin, Benes, Vladimir, Fritsche, Lars G, Weber, Bernhard H. F. and Langmann, Thomas (2010) CRX ChIP-seq reveals the cis-regulatory architecture of mouse photoreceptors. Genome research 20 (11), pp. 1512-25.

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Abstract

Approximately 98% of mammalian DNA is noncoding, yet we understand relatively little about the function of this enigmatic portion of the genome. The cis-regulatory elements that control gene expression reside in noncoding regions and can be identified by mapping the binding sites of tissue-specific transcription factors. Cone-rod homeobox (CRX) is a key transcription factor in photoreceptor ...

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Item type:Article
Date:2010
Institutions:Medicine > Lehrstuhl für Humangenetik
Identification Number:
ValueType
20693478PubMed ID
10.1101/gr.109405.110DOI
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:18227
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