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ABCA10, a novel cholesterol-regulated ABCA6-like ABC transporter.

Wenzel, Jürgen J ; Kaminski, Wolfgang E ; Piehler, Armin ; Heimerl, Susanne ; Langmann, Thomas ; Schmitz, Gerd



Abstract

We recently identified several novel members of the A subclass of ABC transporters. In this study, we report the cloning of an additional ABC A subfamily transporter, denoted ABCA10, from macrophages. The coding sequence of ABCA10 is of 4.6 kb size and codes for a 1543-amino acid protein that bears the structural features of a full-size ABC transporter. Intriguingly, ABCA10 contains a PEST ...

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