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Nucleoside triphosphate pattern of avian embryonic red cells: role of RNA degradation and AMP deaminase/5'-nucleotidase activity

Baumann, Rosemarie ; Götz, Robert ; Dragon, Stefanie



Abstract

During terminal erythroid differentiation, degradation of RNA is a potential source for nucleotide triphosphates (NTPs) that act as allosteric effectors of hemoglobin. In this investigation, we assessed the developmental profile of RNA and purine/pyrimidine trinucleotides in circulating embryonic chick red blood cells (RBC). Extensive changes of the NTP pattern are observed which differ ...

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