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A novel glycosphingolipid that may participate in embryo inversion in Volvox carteri

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Wenzl, Stephan ; Sumper, Manfred
Date of publication of this fulltext: 10 Dec 2010 10:05


Mouse monoclonal antibody 4-I-244 detects a developmentally regulated antigen in embryos of Volvox carteri and inhibits specifically the morphogenetic process of inversion (the process by which the embryo turns inside out). Antigen 4-I-244 was chemically characterized as a complex phytosphingolipid containing the neutral sugars xylose, galactose, and glucose as well as inositol and phosphate.

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