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New inhibitors for the ABCG2 transporter

Fischer, Carolin (2012) New inhibitors for the ABCG2 transporter. PhD, Universität Regensburg.

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Date of publication of this fulltext: 27 Feb 2012 07:14

Abstract (English)

Chapter 1 reviews the copper- and palladium-mediated aryl-N bond formations used in the synthesis of biological active compounds. Examples using the palladium-catalysed Buchwald-Hartwig method, the copper-mediated Ullmann-Goldberg method and the Cham-Lan method were compared concerning their reaction conditions, their scope for a wide spectra of substituent and functional groups and their ...


Translation of the abstract (German)

Kapitel 1 vermittelt einen Überblick über die kupfer- und palladiumvermittelte Aryl-N Bindungsbildung die bei den Synthesen biologisch aktiver Substanzen verwendet wird. Beispiele, die die palladiumkatalysierte Buchwald-Hartwig Methode, die kupfervermittelte Ullmann-Goldberg Methode und die Cham-Lan Methode verwenden, wurden bezüglich ihrer Reaktionsbedingungen, ihrer Toleranz gegenüber ...


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Item type:Thesis of the University of Regensburg (PhD)
Date:27 February 2012
Referee:Prof. Dr. Burkhard König and Prof. Dr. Hans-Achim Wagenknecht
Date of exam:18 February 2011
Institutions:Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König
Interdisciplinary Subject Network:Not selected
Keywords:Organische Synthese, N-Arylierung, ABC-Transporter, ABCG2, Pyrylium Farbstoffe, Dithienylethene, sekundäre Amine, N-Arylation, pyrylium dyes, dithienylethenes, secondary amines
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:19068
Owner only: item control page


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