Regulation of mesenchymal stem cell and chondrocyte differentiation by MIA

DOI zum Zitieren dieses Dokuments:: 10.5283/epub.1938

Tscheudschilsuren, G. ; Bosserhoff, A. K. ; Schlegel, J. ; Vollmer, D. ; Anton, A. ; Alt, V. ; Schnettler, R. ; Brandt, J. ; Proetzel, G.

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Veröffentlichungsdatum dieses Volltextes: 05 Aug 2009 13:34

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Zusammenfassung

Melanoma inhibitory activity (MIA), also referred to as cartilage-derived retinoic acid-sensitive protein (CD-RAP), an 11-kDa secreted protein, is mainly expressed in cartilaginous tissue during embryogenesis and adulthood. Currently, the function of MIA in cartilage tissue is not understood. Here, we describe that MIA acts as a chemotactic factor on the mesenchymal stem cell line C3H10T1/2, ...