MIB-1 and MCM-2 immunohistochemical analysis does not aid in identification of serrated colorectal polyps with abnormal proliferation

Gray, David, Obermann, Ellen C., Evans, Mark, Hartmann, Arndt, Cooper, Kumarasen und Blaszyk, Hagen (2006) MIB-1 and MCM-2 immunohistochemical analysis does not aid in identification of serrated colorectal polyps with abnormal proliferation. American journal of clinical pathology 125 (3), S. 407-412.

PDF Download (659kB) - Nur für Mitarbeiter des Archivs

Zum PubMed-Eintrag dieses Artikels

Zusammenfassung

We investigated the staining characteristics of serrated polyps with abnormal proliferation (SPAP) using MIB-1 and MCM-2 to determine if they could provide assistance in delineating SPAPs from traditional hyperplastic polyps (HPs). Using published morphologic criteria we reviewed H&E slides of 107 polyps from 80 patients. Thirty-nine (36.4%) polyps met the criteria for SPAP Within a given region, ...

Bibliographische Daten exportieren