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MIB-1 and MCM-2 immunohistochemical analysis does not aid in identification of serrated colorectal polyps with abnormal proliferation

Gray, David, Obermann, Ellen C., Evans, Mark, Hartmann, Arndt, Cooper, Kumarasen and Blaszyk, Hagen (2006) MIB-1 and MCM-2 immunohistochemical analysis does not aid in identification of serrated colorectal polyps with abnormal proliferation. American journal of clinical pathology 125 (3), pp. 407-412.

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Abstract

We investigated the staining characteristics of serrated polyps with abnormal proliferation (SPAP) using MIB-1 and MCM-2 to determine if they could provide assistance in delineating SPAPs from traditional hyperplastic polyps (HPs). Using published morphologic criteria we reviewed H&E slides of 107 polyps from 80 patients. Thirty-nine (36.4%) polyps met the criteria for SPAP Within a given region, ...

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Item type:Article
Date:March 2006
Institutions:Medicine > Lehrstuhl für Pathologie
Identification Number:
ValueType
16613344PubMed ID
Keywords:Hyperplastic polyp; Serrated polyp; Serrated neoplasia pathway; MIB-1; MCM-2
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:1943
Owner only: item control page

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