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Molecular profiling of laser-microdissected matched tumor and normal breast tissue identifies karyopherin alpha2 as a potential novel prognostic marker in breast cancer

Dahl, Edgar, Kristiansen, Glen, Gottlob, Kathrin, Klaman, Irina, Ebner, Elke, Hinzmann, Bernd, Hermann, Klaus, Pilarsky, Christian, Dürst, Matthias, Klinkhammer-Schalke, Monika, Blaszyk, Hagen, Knuechel, Ruth, Hartmann, Arndt, Rosenthal, André and Wild, Peter J (2006) Molecular profiling of laser-microdissected matched tumor and normal breast tissue identifies karyopherin alpha2 as a potential novel prognostic marker in breast cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 12 (13), pp. 3950-3960.

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Date of publication of this fulltext: 05 Aug 2009 13:35

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Other URL: http://dx.doi.org/10.1158/1078-0432.CCR-05-2090


Abstract

PURPOSE: The aim of the present study was to identify human genes that might prove useful in the diagnosis and therapy of primary breast cancer. EXPERIMENTAL DESIGN: Twenty-four matched pairs of invasive ductal breast cancer and corresponding benign breast tissue were investigated by a combination of laser microdissection and gene expression profiling. Differential expression of candidate genes ...

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Item type:Article
Date:1 July 2006
Institutions:Medicine > Lehrstuhl für Pathologie
Identification Number:
ValueType
10.1158/1078-0432.CCR-05-2090DOI
16818692PubMed ID
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:1944
Owner only: item control page

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