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Gore, S. ; Baskaran, S. ; König, Burkhard

Efficient Synthesis of 3,4-Dihydropyrimidin-2-ones in Low Melting Tartaric Acid – Urea Mixtures

Gore, S., Baskaran, S. and König, Burkhard (2011) Efficient Synthesis of 3,4-Dihydropyrimidin-2-ones in Low Melting Tartaric Acid – Urea Mixtures. Green Chemistry : GC (13), pp. 1009-1013.

Date of publication of this fulltext: 16 Feb 2011 09:05
Article
DOI to cite this document: 10.5283/epub.19626


Abstract

A general, efficient and green method for the synthesis of dihydropyrimidinones is described under mild conditions employing low melting mixtures of L-(+)-tartaric acid and urea derivatives as a novel reaction medium. The melt plays a triple role: as solvent, as catalyst and as reactant, furnishing highly functionalized dihydropyrimidinones in good to excellent yields.



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Details

Item typeArticle
Journal or Publication TitleGreen Chemistry : GC
Publisher:ROYAL SOC CHEMISTRY
Place of Publication:CAMBRIDGE
Number of Issue or Book Chapter:13
Page Range:pp. 1009-1013
Date2011
InstitutionsChemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König
Identification Number
ValueType
10.1039/c1gc00009hDOI
KeywordsONE-POT SYNTHESIS; SOLVENT-FREE CONDITIONS; BIGINELLI DIHYDROPYRIMIDINE SYNTHESIS; ORGANIC-REACTIONS; SALT MIXTURES; IONIC LIQUIDS; ULTRASOUND IRRADIATION; CONDENSATION; ALKALOIDS; CATALYSIS;
Dewey Decimal Classification500 Science > 540 Chemistry & allied sciences
StatusPublished
RefereedYes, this version has been refereed
Created at the University of RegensburgYes
URN of the UB Regensburgurn:nbn:de:bvb:355-epub-196269
Item ID19626

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