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Colloidal silica nanoparticles for use in click chemistry-based conjugations and fluorescent affinity assays

Achatz, E., Heiligtag, Florian J., Li, Xiaohua, Link, Martin and Wolfbeis, Otto S. (2010) Colloidal silica nanoparticles for use in click chemistry-based conjugations and fluorescent affinity assays. Sensors and Actuators B: Chemical 150 (1), pp. 211-219.

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Date of publication of this fulltext: 18 Mar 2011 06:47

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Abstract

Silica nanoparticles (SiNPs) with an average diameter of 25 nm were prepared by a one-pot method that involves the formation of a silica core that is subsequently covered with a shell functionalized with either azido groups or alkyne groups for use in copper(I)-catalyzed click reactions. Respective triethoxysilane reagents are presented. The SiNPs were (a) rendered fluorescent by click ...

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Item type:Article
Date:21 September 2010
Institutions:Chemistry and Pharmacy > Institut für Analytische Chemie, Chemo- und Biosensorik > Chemo- und Biosensorik (Prof. Antje J. Bäumner, formerly Prof. Wolfbeis)
Identification Number:
ValueType
10.1016/j.snb.2010.07.014DOI
Keywords:Silica nanoparticles; Surface chemistry; Fluorescence; Bioconjugation; Affinity sensing; Biotin; Click chemistry
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Unknown
Created at the University of Regensburg:Unknown
Item ID:19963
Owner only: item control page

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